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What ARA-290 Is Not It is important to clarify what ARA-290 does not do: It is not a painkiller It is not an anabolic peptide It does not stimulate red blood cell production It does not suppress the immune system Its effects are regulatory and restorative , not stimulatory

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Thus, whilst the CVOTs provide valuable and supportive evidence of a benefit of GLP-1 RAs on HF in people with type 2 diabetes, additional trials are required to fully understand the magnitude and nature of such a potential effect, including if it applies to both prevention and treatment of the condition

Gastrointestinal side effects are the most frequently reported adverse reactions with GLP-1 receptor agonists, particularly during the initial weeks of treatment or following dose escalation