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Glutathione peroxidase (GPx) has important functions in the reduction of peroxides that are reported to inactivate vasodilating NO and the decomposition of S-nitrosoglutathione (GSNO), which plays an important role in vascular homeostasis [79]

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Whilst reduced caloric intake is part of the therapeutic goal, it is essential that the calories consumed are nutrient-dense, so that the body continues to receive adequate protein, vitamins, and minerals throughout treatment