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57 GSH depletion occurred without a change in GSSG, suggesting efflux of GSH out of the glia, perhaps with additional increased conversion of GSH to GSSG in response to increased hydrogen peroxide formation

When levels of intracellular ADP & ATP rise to excessive levels, cells pump these nucleotides into the extracellular space as a protective measure, whereupon they are converted consecutively to AMP by CD39 and then AMP is converted to adenosine by CD73 (Figure 8)