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In another report of semaglutide-associated depression [39], the individual had a long history of depression, making it challenging to rule out the interference of disease recurrence

The FDA-approved prescribing information for Mounjaro (tirzepatide for diabetes) does not list anger or irritability as recognized adverse effects

One 2025 review in Osteoporosis International found that GLP-1s enhanced bone remodeling and also decreased bone mineral density over time, leaving the authors to raise questions over the possibility of future bone fractures

Eponiquio C

For measurement of total protein levels on blot, membranes were stained with Ponceau S (Sigma, P7170-1L) for 5 minutes on a shaker (Heidolph Duomax 1030), followed by washing with Milli-Q water