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In the Phase II ZUPREME-1 trial, petrelintide monotherapy produced placebo-adjusted weight loss of up to 9% at 42 weeks, putting it closer to cagrilintide monotherapy from Novo Nordisk A/S (CSE:NOVO-B

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Complementary mechanistic insight is provided by recent work on free-radical-scavenging-nanoparticles, including CQDs, which highlights their ability to attenuate neuroinflammation and oxidative stress through ROS scavenging and suppression of lipid peroxidation, thereby positioning CQDs as both therapeutic nanocarriers and active redox modulators [153]