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It was previously shown that the CBM complex acted as a bridge to transmit the activated TCR signal to the downstream IKK/NF-B and c-Jun N-terminal kinase (JNK) pathways, thereby causing T cell activation (100)

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Unknown Risks with Prolonged Use: As with any treatment, the long-term effects beyond a decade of continuous use are not fully studied, emphasizing the need for periodic medical evaluations

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