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The article explains that semaglutide activates GLP-1 receptors throughout the gastrointestinal tract, slowing gastric emptying and reducing appetite signals, and that the slowdown extends to intestinal motility in a subset of patients
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However, the concentrations achievable through diet alone fall far short of producing the weight loss effects documented in semaglutide clinical trials, where participants lost 1522% of body weight over 68 weeks
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