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Concentrations vary widely based on study design, experimental endpoints, and research model selection

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pneumoniae displayed an impairment in fungal spore germination and hyphal formation followed by downregulation of the transcription factor calcineurin-responsive zinc finger and protein kinase A regulatory subunit (PKAR) encoding genes 16 responsible for regulating conidial germination, hyphal growth and virulence 41,42

Perturbation of NAD + /NADH ratio indicates energy deficiency and is associated with many diseases, including ALS 22

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