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Most medications are automatically refilled for the duration of the enrollment period

In addition, knocking down ACTL6A increased the expression levels of prostaglandin-endoperoxide synthase 2 (PTGS2) (Supplementary Fig 3b), which is a ferroptosis marker 30,46

Clinical trials indicate that percent fat mass drops from a baseline of 4.9% at the lowest dosage of 0.5 mg to as much as 26.1% with 8 mg and 23.2% with 12 mg