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Nausea and diarrhea were common gastrointestinal side effects that occasionally caused people to stop taking the medication

E.Campbell-ThompsonM.GurloT.DawsonD

doi: 10.1056/NEJMoa2403347

Monthly cost for biweekly 500mg injections averages $100$150, which is significantly less than brand-name GLP-1 medications but requires out-of-pocket payment since lipotropic injections are not FDA-approved weight loss drugs and arent covered by insurance

Key Points Thyroid hormones regulate hepatic lipid metabolism in a cell autonomous manner Thyroid hormone receptors (THR and THR) differentially regulate hepatic lipid metabolism Thyroid hormone induces the expression of genes that encode proteins involved in hepatic lipogenesis Thyroid hormone couples autophagy to mitochondrial fat oxidation to induce ketogenesis Thyroid hormone induces reverse cholesterol transport Thyroid hormone analogues and/or mimetics offer therapeutic alternatives for treatment of lipid-associated hepatic pathologies Abstract It has been known for a long time that thyroid hormones have prominent effects on hepatic fatty acid and cholesterol synthesis and metabolism