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Inflammatory Bowel Disease & L-Carnitine Deficiency There are other causes of l-carnitine deficiency besides genetic

Another interesting mechanism of the antioxidant effect of GSH may lay via the activation of cardiac uncoupling proteins (UCPs) (Figure 3A) that mediate H + -leak from intramembrane space of mitochondria into the matrix regulating ATP production via so-called mild uncoupling ( 2 production by the electron transport chain, thus, UCPs are considered protective proteins against oxidative stress ( UCP3 mRNA level that is in agreement with reduced oxidative stress markers in GSH-pretreated old rat hearts

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However, there are some instances where this distinction is not simple

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