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Water retention, mild joint stiffness, and insulin-sensitivity adjustments in the first weeks are also typical and usually settle with dose calibration

To be clear, GLP-1s are not FDA-approved for treating these conditions right now, but if more research proves they are safe and effective, they could receive formal approval for these uses (or others) in the future

However, many people today seek treatments that brighten the skin for reasons entirely unrelated to their ethnicity or race

Though it's not necessary to get skin removed after weight loss, and some choose not to, others find the extra skin troublesome

References Ai X, Yu P, Peng L, et al