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17 Results were expressed as enzyme units per gram of Hb (U/g Hb ): 1 unit represents the amount of enzyme that catalyzes the decomposition of 1 micromole of H 2 O 2 in 1 min at 25 C

Conversely, Nrf2 has been documented to reduce NOX activation and inhibit protein kinase C, consequently leading to a decrease in ROS levels and production in Nrf2-KO mice due to elevated antioxidant GSH levels, highlighting its role in mitigating oxidative stress

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2017 Cell study, with subsequent independent confirmations in human chondrocytes (Huang 2021), mouse Leydig cells (Zhang 2020