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Also, your doctor will likely not prescribe these drugs if you have a condition called multiple endocrine neoplasia syndrome type 2 (MEN 2)

Nishitani S, et al

GLP-1 receptor agonists work by stimulating GLP-1 receptors in the body, which leads to several beneficial effects: Increased insulin secretion: GLP-1 receptor agonists promote insulin release from the pancreas, helping to lower blood sugar levels Reduced glucagon secretion: These medications inhibit the release of glucagon, a hormone that increases blood sugar levels, thereby reducing glucose production Slowed gastric emptying: GLP-1 receptor agonists slow down the emptying of the stomach, leading to increased feelings of fullness and reduced appetite Additionally, tirzepatide, the active ingredient in Mounjaro works on GIP receptors

Slow titration is the most effective way to reduce side effect burden for either medication

More details in our compounded semaglutide with B12 dosage chart