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Tesamorelin is a synthetic 44-amino-acid polypeptide analogue of Growth Hormone-Releasing Hormone (GHRH) 1 with modifications to improve stability and pharmacokinetics compared to native GHRH

While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has also been rising

Rao SV, ODonoghue ML, Ruel M, et al

One study showed faster walk speed, greater muscle strength measured by handgrip dynamometry and higher fat free mass measured by bioimpedance (adjusted for height squared) in DPP4 users than those on sulphonylureas [147], although it is unclear whether this was due to beneficial effects of DPP4 inhibitors or deleterious effects of sulphonylureas

It should only be used by trained research professionals