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FDA-approved in 2014 for treating type 2 diabetes, its taken as a once-weekly injection that lowers blood sugar when combined with a healthy diet and regular exercise

In the PIONEER-6 study, proliferative retinopathy and macular edema requiring treatment were exclusion criteria

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Fresh, sterile supplies reduce the risk of infection and make injections more comfortable

By leveraging germline genetic variants as instruments, MR minimizes confounding from sociodemographic, behavioral, and health-related factors, providing more reliable causal estimates 18,19