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Analysis of GLP-1sensitive metabolic parameters revealed that reduction of food intake in response to acute semaglutide administration was not different in Glp1r VSM+/+ versus Glp1r VSM/ mice (Figure 1N)

In addition to serving as metabolic inhibitor of cytochrome P450 2D6 [21], bupropion enhances monoaminergic function as a norepinephrinedopamine reuptake inhibitor and is approved to treat MDD (target dose 300 mg/day, maximum dose 450 mg/day) [136, 137]

Younes, orcid.org/0000-0003-0929-1003

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