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137,138 ERS Continuous insulin production and secretion in cells under chronic hyperglycemia and IR result in the overload of protein folding machinery and the accumulation of excessive misfolded or unfolded proteins in the ER, therefore triggering UPR and the ERS

271, 1748517490.10.1074/jbc.271.29.17485 29 MadamanchiN

Weeks 7-8: Final phase of standard protocols