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The mitochondrial transmission of the mutation causing the disorder entails a certain probability that the maternal ovum contains and can pass on normal mitochondria in addition to mutated mitochondria

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Additionally, as previously discussed, in the FY 2022 IPPS/LTCH PPS final rule (86 FR 44975 through 44979), we finalized a 1-year extension of new technology add-on payments for FY 2022 in light of the unique circumstances associated with ratesetting for FY 2022, for which CMS finalized the use of the FY 2019 MedPAR data instead of the FY 2020 MedPAR data to develop the FY 2022 relative weights