When looking at the endogenous NAD + fluxes at the systemic level, most organs do not synthesize NAD + de novo, but can utilize NAM made in the liver 39
Gharibshahian M, Torkashvand M, Bavisi M, Aldaghi N, Alizadeh A
Research in aging rats demonstrated that Epithalon treatment significantly increased activities of key antioxidant enzymes including superoxide dismutase (SOD), glutathione peroxidase (GPX), and glutathione-S-transferase
E., Pastoor, T., Dellarco, V
[21] clearly showed that at least -GST isoform is present, both inside the nucleus and in the outer nuclear membrane, suggesting that GST plays a major protective role in the nucleus against alkylating compounds and organic peroxides