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This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked

Among 26,080 individuals with PD, there was no significant association between smoking status and all-cause mortality in a nationwide cohort study (ex-smoker, HR 0.1.03, 95% CI 0.971.10

Human CSF samples Samples were obtained from the Mass General Institute for Neurodegenerative Disease (MIND) biorepository, which includes CSF collected with research use consent at the time of diagnostic lumbar punctures at the Department of Neurology at Massachusetts General Hospital (IRB: 2015P000221)

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Urinalysis: A visual and chemical examination of urine, most often used to screen for urinary tract infections and kidney disease