allulose stimulates glp 1 as a GLP-1-Like Sugar: Mechanisms and Therapeutic Implications Is Allulose a GLP-1 Agonist?

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Over the following decades, Pickart (who passed away in 2023 at age 85) and collaborators documented GHK-Cu's effects on wound healing, collagen production, hair growth, nerve outgrowth, and inflammation, building a substantial body of evidence that the peptide functions as a systemic tissue repair signal rather than having effects limited to any single tissue type

doi: 10.1016/j.biopha.2023.114606 89 TotoAWildPGrailleMTurcuVCrzCHemmendingerMet al

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Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice