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In addition to discussing the weight loss efficacy of semaglutide, the recently published results of CV outcome trials will be addressed later in this paper

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Seek immediate medical attention (call 999 or attend A&E) if you develop: Severe, unrelenting abdominal pain Signs of severe dehydration with confusion or altered consciousness Persistent vomiting with inability to retain any fluids for more than 24 hours Chest pain or difficulty breathing alongside gastrointestinal symptoms For patients with diabetes taking GLP-1 medications, persistent vomiting poses additional risks

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