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An increase in GST activity suggests increased GSH demand for conjugation reactions, where conjugation itself regulates GSH synthesis by increasing -GCS transcription (12)

Teas J, Hurley TG, Hebert JR, Franke AA, Sepkovic DW, Kurzer MS

Dig Dis Sci 53(11):30183025 Malaguarnera M, Vacante M, Giordano M, Motta M, Bertino G, Pennisi M, Neri S, Malaguarnera M, Li Volti G, Galvano F (2011a) L-carnitine supplementation improves hematological pattern in patients affected by HCV treated with Peg interferon-alpha 2b plus ribavirin

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Longer-standing issues and partial tears may need six to eight weeks of consistent treatment