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Given that this is an investigational treatment, clinical trials are necessary to evaluate the efficacy and safety of the long-acting PYY analog, as indicated by the forthcoming Phase 1 SAD/MAD data expected in 2025

however, the long-term safety profile remains undefined

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GLP-1RAs exert multiple anti-atherosclerotic effects contributing to stroke prevention such as enhanced plaque stability, reduced vascular smooth muscle proliferation, increased nitric oxide, and improved endothelial function

A supervised taper over 48 weeks allows your brain to gradually increase satiety thresholds and your gut hormones to normalize more smoothly