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sales volumes for cigarettes and pouches so FDA can measure substitution versus net new uptake, said Dr

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Baseline assessment Remote informed consent will be obtained by the Research Coordinator before any data is collected

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The increase in sphingomyelins can interfere with signaling pathways, including phosphatidylinositol 3-kinase (PI3K)/AKT and MAPK, inhibiting cancer cell proliferation and growth (222)