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Moreover, the job of the liver has evolved to protect us from the remarkably diverse and potentially harmful chemicals we consume in our diets, and in this regard, a drug is just another nonfood or non-nutrient to be inactivated and removed

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Exposure of adult mice to environmental tobacco smoke fails to enhance the immune response to inhaled antigen

Limitations also apply to Kenkel et al.s analysis, however, due to the observational nature of the data and the small sample size of adults who used ECs but never smoked (N = 12) [28]