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Studies focusing on in vitro , in vivo , or clinical evaluations of mechanistic pathways, therapeutic potential, or delivery strategies were included, while those addressing synthetic flavonoids, non-AD models, or lacking mechanistic relevance were excluded

10.14218/JCTH.2015.00052 61 ZhangM.TangZ

These scaffolds were then impacted following the same method described above

However, retinoids offer additional benefits including texture improvement and dark spot reduction that copper peptides don't provide as strongly

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