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on the other hand, elevated levels of xanthine oxidase may lead to increased production of reactive oxygen species, which in turn increases lipid peroxidation reactions, aggravating the great damage to cells increasing cell turnover thus leading to increased purine catabolism and thus increased uric acid production 25

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Cannabis can inhibit certain cytochrome P450 enzymes, which may cause antidepressants to remain in the body longer than intended

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