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Yes, Ozempic can affect hormones, but only certain ones

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For instance, a patient who has hit a weight plateau with metformin might benefit from the addition of an appetite suppressant like phentermine or the combination of phentermine/topiramate to counteract the increase in hunger often caused by elevated ghrelin levels following significant weight loss through dietary changes

Wharton S, Lingvay I, Bogdanski P, et al

3.5 Impact on Cardiovascular Risk Factors It improves lipid profiles, reduces body weight, and lowers blood pressure