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More signal, less interference

Renal, Cardiovascular, and Safety Outcomes of Canagliflozin by Baseline Kidney Function: A Secondary Analysis of the CREDENCE Randomized Trial

Already, many GLP-1 users quit within a year, studies suggest often due to side effects, high costs, or insurance issues

The enhanced mitochondrial oxidative stress leads to DA oxidation with generation of DAQs, conjugation of DAQs with GBA1, inhibition of GBA1 enzymatic activity, lysosomal dysfunction, and accumulation of deleterious -syn protein [10]