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The precise mechanism may involve multiple processes including compensatory receptor crosstalk and it is to be further investigated

2023;24:e57268

Since first isolated from broccoli and demonstrated to have cancer chemoprotective properties in rats in the early 1990s, over 3000 publications have described its efficacy in rodent disease models, underlying mechanisms of action or, to date, over 50 clinical trials examining pharmacokinetics, pharmacodynamics and disease mitigation

Scholar Zhang Q, Bykov VJN, Wiman KG, Zawacka-Pankau J

With vitamin C, your skin will gradually return to its baseline as existing brightening effects fade, but the protective benefits against sun damage provide lasting value