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The rise in e-cigarette use corresponds with the rise in marketing and availability of e-cigarette devices such as JUUL, which dispense nicotine via liquid refill pods available in flavors including strawberry and cotton candy, said Brian King, MPH, PhD, deputy director for research translation at the CDCs Office on Smoking and Health

He recounts his own experience to make the point

Shown in the middle: Nicotinic acid undergoes phosphoribosylation catalyzed by nicotinic acid phosphoribosyltransferase (NAPRT) to form nicotinic acid mononucleotide

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We compared the estimates for 2011 from the combined sample (the second model) to the estimates for the landline sample (the first model) to derive county-level measures of the bias introduced by not including wireless-only respondents in 2011