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For former heavy smokers taking CYP1A2-metabolized drugs, dose adjustments after cessation are essential to avoid elevated drug levels and adverse drug reactions (ADRs)

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Although the exact mechanism of action is not fully understood, clofazimine seems to interfere with cellular membrane functions, including ion transport and respiration, ultimately causing Mtb death (Cholo et al., 2017

In 1997, according to the book Write It When I'm Gone , by Thomas DeFrank, Ford told the author, "I haven't had a drink in twenty-two years, she [Betty] hasn't had one in twenty-three years