In contrast, our real-world cohort, without strict eligibility restrictions, may capture risk emerging in specific subpopulations
Diabetes mellitus (DM) is a major risk factor CVDs and is also associated with a higher risk of graft failure [5, 6]
GLP-1RAs inhibit RGC apoptosis in glaucoma through GABAergic signaling, but their role in AMD, characterized by oxidative stress and choroidal neovascularization, needs further investigation (Shao et al., 2024)
Similarly, four weeks of chronic unpredictable mild stress in male mice reduces microglial KMO via corticosterone, increasing hippocampal KYNA and producing depressive-like behaviours that are rescued by nicotine-mediated 7nAChR activation [72]
Inability to convert B12 to a usable form As is mentioned above, there are polymorphisms (MTHFR, MTRR) that can inhibit the body from converting B12 to a usable form