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The cells were washed with serum-free medium three times to remove excess DCFH-DA and immediately analysed using the FACSCanto II flow cytometer

Our data indicate that nucleosome-binding of Sirt7 through its C -terminal basic region is critical for efficient H3K36/37 deacylations on nucleosome

While this is great for managing caloric intake, these receptors are also located in areas of the brain that regulate thirst

doi:10.1056/NEJMoa2301972 Frias JP, Nauck MA, Van J, et al