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Marlboro was introduced in the 1920s as a womans cigarette with advertising slogans such as, Mild as May and Red tips for your pretty lips. In the 1950s, under the direction of marketing expert George Weisman and the advertising firm of Leo Burnett, Marlboro achieved enormous appeal when the company emboldened the packages design with a medallion like chevron and revamped the image to one of rugged cowboys in the wide-open spaces, television commercials for which were accompanied by the theme song from the film The Magnificent Seven

Though it was not the focus of our study, we also examined limited and partial smoking bans

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There are also important epigenetic effects of cigarette smoke exposure mediated by aberrant microRNA expression and DNA methylation patterns in target tissues

The V-Type line featured all of Halos most popular flavors at launch, and more flavors are gradually being added