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Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football

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Phytoconstituents targeting HGF, urokinase-type plasminogen activator, IGF-1, fibrinogen alpha chain, leptin, and its receptor Quercetin can suppress HGF signaling by suppressing the AKT pathway [224] and resveratrol can suppress mRNA expression of urokinase plasminogen activator [225]

184,185,186,187 Interactions with other pathways GLP-1 not only promotes the release of insulin but also enhances the response of pancreatic -cells to insulin through the PI3K/Akt pathway, thereby improving insulin signal transduction and increasing the sensitivity of peripheral tissues to insulin

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