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A recent publication from JAMA on the analysis of people who have been taking GLP-1 agonists from 2006 to 2020 shows that people who are taking GLP-1 agonists have a nine-fold higher risk of developing acute pancreatitis compared with the older drug for weight loss, bupropion, and four times more frequent intestinal obstruction and three times more frequent gastroparesis

For vitamin B12 deficiency, patient was initiated on intramuscular cyanocobalamin 1000 mcg once daily

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It may help restore the muscle architecture and vascular density needed to handle normal exertion though patients with PEM should approach any intervention with careful pacing and clinical oversight

Natural history, phenotypic spectrum, and discriminative features of multisystemic RFC1 disease