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These covariates include (1) the e-cigarette product (e.g., type of device, nicotine content and delivery, flavorings or other contents of the e-liquid), (2) pattern of current use (e.g., frequency of use, duration of use), and (3) user characteristics (particularly interest in quitting and prior history of e-cigarette use, but also demographics and smoking history) (Malas et al., 2016)

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This creates a soothing and cooling effect on the throat and airways, making the smoke feel less harsh and easier to inhale