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Reduced REM leads to irritability, poor focus, and emotional instability

Long-Term Impact on the SleepWake System Nicotine exposure over years can desensitize key receptors in the brain responsible for regulating the circadian rhythm - the natural 24-hour sleepwake cycle

After analyzing the physical characteristics and chemicals in the smoke and tobacco filler in 13 varieties of American Spirit cigarettes, researchers found that American Spirit cigarettes generally have more tobacco filler, and, as a result, produce a higher number of puffs which may expose the brands smokers to more tobacco chemicals per cigarette than smokers of other brands

Allergen Notice: Products in our stores may contain, or may have been exposed to, one or more of the following allergens: peanuts, tree nuts, sesame, milk, eggs, wheat, soy, fish and crustacean shellfish.

Pouch Size: Regular/Large