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Activation of the TMAO-induced endothelial NLRP3 inflammasome was reduced by a mitochondrial ROS scavenger or SIRT3 overexpression in human umbilical vein endothelial cells (HUVECs), which suggested that the activation was mediated in part by inhibition of the SIRT3-SOD2-mtROS signaling pathway (Chen et al., 2017)

Protein sources: Eggs, fish, and lean meats provide the amino acids needed for glutathione synthesis

The antizyme 1 mRNAs contain two overlapping open reading frames (ORFs)

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10.1177/039463201202500123 Therapy 27 MahzouniehM.KhoshnoodS.EbrahimiA.HabibianS.YaghoubianM