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9 In reaching this conclusion, the Appellate Body treated this as a case of de facto , not de jure , discrimination

There is no safe level of exposure to a cancer-causing agent

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This exercise yielded 194 statistically significant changes (compared to the 26 reported in PM's published paper, Text S1,Table S-3), suggesting that a better powered study would have detected a much broader range of biological effects associated with the additives than identified in PM's published paper [18], suggesting that it substantially underestimates the toxic potential of cigarette smoke and additives

We included all relevant clinical studies that enrolled chronic smokers and nonsmokers in whom arterial stiffness was measured