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All procedures and the experimental design were approved by the Ethical Committee for Animal Research of the Federal University of Ouro Preto (Protocol n 2015/35), according to the Brazilian Society of Neuroscience and Behaviour and the National Institutes of Health Guidelines for the Care and Use of Laboratory Animals (8th edition, 2011)

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Opponents, led by faith-based groups like the Catholic Church, have opposed the proposition by raising $2.35 million, with the Diocese of Pueblo contributing $135,000 in the latest reporting period