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Although neither of these trials specifically targeted CHE nor demonstrated a significant reduction in OHE, many of the enrolled patients were likely to have CHE, and the results of the LiveSMART trial suggest potential clinical benefits of CHE-directed therapy beyond OHE prevention

By disrupting the blood supply to tumors, BPC-157 limits their ability to grow and spread

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Targeting the Melanocortin System to Treat Hereditary Obesity Table 3: Selected genetic causes of obesity Setmelanotide, an MC4R agonist and first-in-class treatment for hereditary obesity Drug Development Pipeline for Genetic Causes of Obesity 6