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Other less common causes include certain medications (such as corticosteroids, methotrexate, amiodarone, valproate, and some antiretroviral drugs), viral hepatitis, rapid weight loss, malnutrition, and rare genetic conditions affecting fat metabolism

FDA as NRTs, with a HPHC profile far superior to combustible cigarettes [16], have been available in the U.S

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An estimated 90% of lung cancer cases are thought to be caused by smoking[viii]