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A Philip Morris spokesperson noted that the US Food and Drug administration has said many of the serious health concerns associated with tobacco are from its smoke, not the nicotine itself

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The researchers compared healthy, young-adult smokers aged 18 to 38 who were regular users of e-cigarettes or tobacco cigarettes

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The new warnings carry messages such as Smoking reduces blood flow to the limbs, which can require amputation, and Smoking causes bladder cancer, which can lead to bloody urine. New warnings will occupy 50% of the pack area The 11 finalized cigarette health warnings represent the most significant change to cigarette labels in more than 35 years and will considerably increase public awareness of lesser-known, but serious negative health consequences of cigarette smoking, said director of the FDAs Center for Tobacco Products, Mitch Zeller