This is, then, oxidized by cytosolic isocitrate dehydrogenase 1 (IDH1) to -ketoglutarate with the production of NADPH required for the detoxification from reactive oxygen species (ROS
The mechanism of action is unclear possibly by preventing tau protein aggregation or increasing amyloid- clearance by enhancing proteasome activities [19,20]
doi: 10.1016/S0197-0186(96)00025-3
Key Ingredients Water, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Cetyl Ethylhexanoate, Propanediol, Pentaerythrityl Tetraisostearate, Niacinamide, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Vinyl Dimethicone, Hydrogenated Lecithin, Saccharide Hydrolysate, Ethylhexylglycerin, Adenosine, Niacinamide, Bakuchiol, 3-O-Ethyl Ascorbic Acid, Houttuynia Cordata Extract, Glutathione (5 ppm), Myosotis Sylvatica Flower/Leaf/Stem Extract, Oenothera Biennis (Evening Primrose) Flower Extract
[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Surez-Rivero J.M., Pastor-Maldonado C.J., Povea-Cabello S., lvarez-Crdoba M., Villaln-Garca I., Munuera-Cabeza M., Surez-Carrillo A., Talavern-Rey M., Snchez-Alczar J.A