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Its metabolism is closely linked to the transsulfurization branch (providing cysteine), the GSH-GSSG redox cycle (maintaining redox balance), and the detoxification system (completing substance detoxification), forming a complex and efficient metabolic network

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While this constitutive activity alone gives support to a role of GHSR1a centrally where only extremely low levels of ghrelin have been found (Hosoda et al., 2000

Notably, LBs have also been observed in several other neurological disorders, including dementia with Lewy bodies, the LB variant of Alzheimers disease, infantile neuroaxonal dystrophy, HallervordenSpatz syndrome, subacute sclerosing panencephalitis, and Down syndrome

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