Scientific studies have suggested that other cannabinoids like CBD may also play a significant role in its psychoactive effects
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Smoking, nicotine, and ACE2 On one hand, it is proposed that smoking or nicotine may upregulate the detrimental angiotensinconverting enzyme (ACE) but downregulate the compensatory ACE2/ANG(17) receptor axis and hence contribute to cardiovascular and pulmonary diseases [53, 54, 55]
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However, a recent study published in the Journal of Hazardous Materials, titled The lure of Healthier Smoke: Comparative physical, chemical, and oxidative potential characterisation of emissions from herbal and tobacco cigarettes , co-authored by Alok Kumar Thakur and Sameer Patel from IIT Gandhinagar (IITGN) and PS Ganesh Subramanian and Vishal Verma from the University of Illinois, Urbana-Champaign, US, found that the claims are misleading